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 New Mexico AIDS InfoNet

Fact Sheet Number 502

CRYPTOSPORIDIOSIS


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WHAT IS CRYPTOSPORIDIOSIS?

Cryptosporidiosis (Crypto) is an infection. It is caused by the

parasite Cryptosporidium parvum. Parasites get their nutrients

from another living organism (the host). Crypto mainly affects

the intestines and causes diarrhea.

Crypto is easily spread by contaminated food or water, or direct

contact with an infected person or animal. About 15% to 20% of

people with AIDS are infected with crypto. Only some of these

infections lead to serious disease.

Crypto causes diarrhea, nausea, vomiting, and stomach cramps.

In people with healthy immune systems, these symptoms do not last

more than about a week. See Fact Sheet

554 for more information on diarrhea.

However, crypto may continue for a long time if the immune

system is damaged. This usually happens with T-cell

counts below 300. If crypto continues for 4 weeks or more

insomeone with HIV, they have AIDS according to the guidelines

of the Centers for Disease Control.

Diarrhea can interfere with the absorption of nutrients. If

it continues for a long time, you can develop serious weight loss

(wasting, see Fact Sheet 518).

Several diseases cause similar problems. To confirm a diagnosis,

doctors usually check your stool (bowel movement) for parasites

and their eggs. This is called an “O and P” or “ova

and parasites” test.


CAN CRYPTO BE

PREVENTED?

There is no medication that prevents crypto.

The best protection is cleanliness. Avoid contact with human

or animal wastes. Wash your hands after using the bathroom, gardening,

handling dirty laundry or animals, or changing diapers. Crypto

can be transmitted through oral-anal sexual activity. Swallowing

or swimming in water contaminated with human or animal waste can

also expose you. Raw oysters may carry crypto.

In some cities the public water supply is contaminated with

crypto. Check with your water department. If there is a problem,

and if your T-cell count is below 300, consider the following

steps:

  • Boil drinking or cooking water for one minute; or
  • Drink bottled water; or
  • Drink filtered water: Use a home filter labeled “1-micron

    filter” or “Meets National Science Foundation (NSF)

    standard number 53 for cyst removal;” or

  • Drink distilled water. Bottled water may not be safe unless

    it has been boiled or filtered correctly.


HOW IS CRYPTO

TREATED?

There is no drug treatment that clears up crypto. Several drugs

are being tested. These include paromomycin (Humatin), azithromycin

(Zithromax), latrazuril, and atovaquone (Mepron).

The most promising drug to fight crypto is nitazoxanide. It

helped about half of the people who took it in a research study.

Unfortunately, development of nitazoxanide was stopped after the

FDA withheld approval of the drug.

We can’t get rid of the crypto infection. However, there are

ways to control the diarrhea it causes. These include Imodium,

Kaopectate, and similar preparations. Serious, ongoing diarrhea

is sometimes treated with Sandostatin.

Another product, bovine colostrum concentrate (Sporidin-G),

is being tested for controlling diarrhea caused by crypto.


THE BOTTOM LINE

Cryptosporidium is a fairly common parasite.

It is found in animals, humans, soil, and water. It can be transmitted

easily.

In people with normal immune systems, crypto causes diarrhea

and other stomach problems for about a week. In people with less

than 300 T-cells, the diarrhea may continue.

The best way to prevent infection by crypto is frequent hand

washing. If your local water supply is contaminated with crypto,

use only boiled or filtered water for cooking and drinking.

Several drugs are being studied to fight crypto, but none are

approved yet.

Chronic diarrhea due to crypto should be controlled in order

to avoid more serious problems like wasting.


Reviewed November 24, 2002

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